SCP2D1

Across TCGA pan-cancer cohorts, SCP2D1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated SCP2D1 data layer compared with 7 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SCP2D1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SCP2D1 expression acts as an unfavorable survival marker.

KIRC, SKCM, and MESO are the cancer types where SCP2D1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.760	0.879	<.001	84	view →
SKCM	OS	Tertile	III,IV	0.174	0.708	<.001	78	view →
MESO	OS	Tertile	III,IV	0.098	0.579	.001	72	view →
UCEC	OS	Tertile	All	0.790	0.927	.015	42	view →
THYM	DFS	Tertile	All	0.091	0.884	<.001	36	view →
SCLC	DFS	Tertile	All	0.164	0.826	<.001	18	view →
OV	DFS	Tertile	III,IV	0.386	0.537	.035	18	view →
UCS	OS	Tertile	All	0.258	0.694	.008	18	view →
SARC	DFS	Tertile	All	0.113	0.355	.004	15	view →
LGG	OS	Tertile	All	0.657	0.912	.003	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

SCP2D1–KIRC (OS)

Open the KIRC breakdown →