SCP2D1

Across TCGA cell cohorts, SCP2D1 RNA expression is significantly associated with the mutation status of many other genes, with 18 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SCP2D1-associated genes across cancer lineages are ARHGAP22, MDC1, and ZNF618. Each is linked with SCP2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCP2D1-to-partner and partner-to-SCP2D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARHGAP22 grouped by SCP2D1-low versus SCP2D1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCP2D1→partner) and Y-score (partner→SCP2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ARHGAP22 →	+5.357	+0.070	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	MDC1 →	+4.357	+0.052	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZNF618 →	+4.357	+0.052	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZNF770 →	+4.357	+0.052	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	KLHL23 →	+5.357	+0.070	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ZNF658 →	+4.357	+0.052	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

ARHGAP22 by SCP2D1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →