SCP2D1-AS1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SCP2D1-AS1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SCP2D1-AS1-associated genes across cancer lineages are CCL19, OR1P1, and OR8B4. Each is linked with SCP2D1-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCP2D1-AS1-to-partner and partner-to-SCP2D1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL19 grouped by SCP2D1-AS1-low versus SCP2D1-AS1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCP2D1-AS1→partner) and Y-score (partner→SCP2D1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADCCL19 →+0.076+4.887.001.00931
LUNG_NSCLC_LUADOR1P1 →+0.027+4.887.007.00931
LUNG_NSCLC_LUADOR8B4 →+0.027+4.887<.001.00931
LUNG_NSCLC_LUADSCYGR8 →+0.022+5.662<.001.00231
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CCL19 by SCP2D1-AS1 expression — LUNG_NSCLC_LUAD

Box plot of CCL19 in SCP2D1-AS1-low vs SCP2D1-AS1-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration