Across TCGA pan-cancer cohorts, SCOC-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SCOC-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SCOC-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated SCOC-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and PAAD show a favorable association.

KIRP, PAAD, and LIHC are the cancer types where SCOC-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	II,III,IV	0.781	0.287	.001	60	view →
PAAD	OS	Tertile	All	0.611	0.243	<.001	59	view →
LIHC	DFS	Median	All	0.357	0.500	<.001	56	view →
READ	OS	Quartile	All	0.865	0.412	.001	46	view →
UVM	DFS	Quartile	All	0.860	0.511	.007	35	view →
ACC	OS	Median	II,III,IV	0.880	0.642	.003	33	view →
UCS	DFS	Tertile	II,III,IV	0.623	0.153	.002	30	view →
KIRC	DFS	Tertile	II,III,IV	0.417	0.603	.007	25	view →
CESC	OS	Quartile	All	0.786	0.369	.018	24	view →
KICH	OS	Median	All	0.717	1.000	.009	18	view →
THCA	OS	Median	All	0.961	1.000	.006	11	view →
GBM	OS	Median	All	0.237	0.468	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

Exploration

Same gene, other analysis: SCOC-AS1 tumor-vs-normal RNA expression · all SCOC-AS1 data types