Q-omics provides the consensus-scored SCOC-AS1 profile across patient tissues and cancer cell-line models. SCOC-AS1 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, SCOC-AS1 is differentially expressed in 13, with the highest sampling consensus in KIRC. Additionally, SCOC-AS1 RNA expression shows 16,609 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRP, KIRC, and THYM as cancer lineages where SCOC-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SCOC-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SCOC-AS1 survival associations across molecular data types. SCOC-AS1 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SCOC-AS1 RNA expression–survival associations across cancer types. High SCOC-AS1 expression shows unfavorable associations in LIHC, but favorable associations in KIRP, PAAD, READ, UVM and ACC. The KIRP Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify KIRP as the clearest survival context for SCOC-AS1 RNA expression.
This table summarizes SCOC-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for SCOC-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SCOC-AS1 shows lower tumor expression in THCA, LUAD and LUSC and higher tumor expression in KIRC, LIHC and KIRP. The KIRC box plot shows higher SCOC-AS1 RNA expression in tumor versus normal tissue (log2 FC = +0.193, t-test p < 0.001).
This table shows molecular features associated with SCOC-AS1 in patient tissues and cancer cell lines. In patient samples, SCOC-AS1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
