SCNN1G

Across TCGA cell cohorts, SCNN1G RNA expression is significantly associated with the go_rna of many other GO terms, with 3,077 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SCNN1G-associated GO terms across cancer lineages are Response to indole-3-methanol, Endosome organization, and Positive regulation of skeletal muscle fiber development. Each is linked with SCNN1G in more than 5 cancer types. Because this analysis shows association rather than direction, both SCNN1G-to-partner and partner-to-SCNN1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by SCNN1G-low versus SCNN1G-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCNN1G→partner) and Y-score (partner→SCNN1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Response to indole-3-methanol →	+0.247	+1.587	<.001	.008	3	6
LUNG_SCLC	Endosome organization →	+0.063	+0.986	<.001	.009	3	6
SOFT_TISSUE	Positive regulation of skeletal muscle fiber development →	-1.468	-0.584	<.001	.007	3	5
UPPER_AERODIGESTIVE_TRACT	Response to thyroid hormone →	+0.090	+1.342	.003	.001	2	6
BONE	Negative regulation of RNA catabolic process →	+0.055	+2.274	<.001	.002	3	5
BONE	Negative regulation of mRNA catabolic process →	+0.059	+2.517	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,077 associations by consensus.

Response to indole-3-methanol by SCNN1G expression — BREAST

Explore this box plot interactively →