SCNM1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SCNM1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,205 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SCNM1-associated genes across cancer lineages are RFC4, CENPA, and HJURP. Each is linked with SCNM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SCNM1-to-partner and partner-to-SCNM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCNM1 versus RFC4 in GBM, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCNM1→partner) and Y-score (partner→SCNM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRFC4 →+0.790+0.521.008.00634
LSCCCENPA →+0.765+0.478<.001.00233
OVHJURP →+1.246+0.825.002<.00133
OVHROB →+1.218+0.825.003<.00124
OVKIF23 →+1.674+0.825.001<.00133
OVKIF11 →+1.386+0.825<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,205 associations by consensus.

SCNM1 vs RFC4 — GBM

Per-sample scatter of SCNM1 vs RFC4 in GBM (Pearson r = 0.55).

Explore this scatter interactively →

Exploration