Across TCGA cell cohorts, SCN5A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,510 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SCN5A-associated GO terms across cancer lineages are RNA localization, Protein K11-linked ubiquitination, and Regulation of mRNA stability. Each is linked with SCN5A in more than 11 cancer types. Because this analysis shows association rather than direction, both SCN5A-to-partner and partner-to-SCN5A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN5A→partner) and Y-score (partner→SCN5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	RNA localization →	+0.148	+0.956	<.001	.003	3	12
OESOPHAGUS	Protein K11-linked ubiquitination →	+0.070	+0.501	.001	.007	3	11
SOFT_TISSUE	Regulation of mRNA stability →	+0.065	+1.299	<.001	<.001	3	10
OESOPHAGUS	Nucleic acid transport →	+0.129	+0.743	<.001	.003	3	10
OESOPHAGUS	RNA transport →	+0.129	+0.743	<.001	.003	3	10
BLOOD_Leukemia	Regulation of mitotic metaphase/anaphase transition →	+0.072	+0.503	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,510 associations by consensus.

Exploration

SCN5A survival (RNA) · tumor vs normal (RNA) · all SCN5A data types