SCN4B

Across TCGA patient cohorts, SCN4B protein abundance is significantly associated with the RNA expression of many other genes, with 1,973 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCN4B-associated genes across cancer lineages are PDCD5, ASPA, and PEBP4. Each is linked with SCN4B in more than 1 cancer types. Because this analysis shows association rather than direction, both SCN4B-to-partner and partner-to-SCN4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCN4B versus PDCD5 in LSCC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN4B→partner) and Y-score (partner→SCN4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PDCD5 →	-0.585	-0.440	.001	.003	3	2
GBM	ASPA →	+1.191	+0.811	<.001	.001	3	2
LSCC	PEBP4 →	+1.716	+0.375	<.001	.004	3	2
GBM	FAM189A2 →	+1.029	+0.951	.001	<.001	3	2
LUAD	ADD3 →	+0.597	+0.650	.003	.006	3	2
LSCC	HSPB8 →	+0.837	+0.387	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,973 associations by consensus.

SCN4B vs PDCD5 — LSCC

Explore this scatter interactively →