SCN4B

Across TCGA cell cohorts, SCN4B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,066 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SCN4B-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of respiratory burst involved in inflammatory response, and Negative regulation of respiratory burst. Each is linked with SCN4B in more than 10 cancer types. Because this analysis shows association rather than direction, both SCN4B-to-partner and partner-to-SCN4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by SCN4B-low versus SCN4B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN4B→partner) and Y-score (partner→SCN4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.081	+0.416	.002	<.001	3	11
CNS	Negative regulation of respiratory burst involved in inflammatory response →	+0.063	+1.211	.003	.001	3	9
CNS	Negative regulation of respiratory burst →	+0.063	+1.211	.003	.001	3	9
LARGE_INTESTINE	Negative regulation of response to endoplasmic reticulum stress →	+0.089	+0.117	<.001	.009	3	8
SKIN	Cellular respiration →	+0.062	+0.430	<.001	<.001	3	8
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.082	+0.423	.004	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,066 associations by consensus.

Regulation of myoblast fusion by SCN4B expression — OVARY

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