SCN3B

Across TCGA patient cohorts, SCN3B protein abundance is significantly associated with the RNA expression of many other genes, with 3,195 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCN3B-associated genes across cancer lineages are YPEL1, SNRPD3, and GRK3. Each is linked with SCN3B in more than 1 cancer types. Because this analysis shows association rather than direction, both SCN3B-to-partner and partner-to-SCN3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCN3B versus YPEL1 in GBM, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN3B→partner) and Y-score (partner→SCN3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YPEL1 →	+0.466	+0.483	.007	.008	3	1
GBM	SNRPD3 →	+0.391	+0.622	.007	.007	3	1
GBM	GRK3 →	+0.630	+0.638	<.001	<.001	3	1
GBM	SOX10 →	+1.503	+0.676	<.001	<.001	3	1
GBM	SLC16A8 →	+0.542	+0.463	<.001	<.001	3	1
GBM	SEPTIN3 →	+0.759	+0.541	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,195 associations by consensus.

SCN3B vs YPEL1 — GBM

Explore this scatter interactively →