SCN3B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SCN3B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,931 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SCN3B-associated GO terms across cancer lineages are Regulation of translational initiation, Regulation of organelle assembly, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with SCN3B in more than 9 cancer types. Because this analysis shows association rather than direction, both SCN3B-to-partner and partner-to-SCN3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by SCN3B-low versus SCN3B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN3B→partner) and Y-score (partner→SCN3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYRegulation of translational initiation →+0.079+0.436.003.005310
OVARYRegulation of organelle assembly →+0.039+0.460<.001.00339
KIDNEYRegulation of syncytium formation by plasma membrane fusion →+0.100+0.520<.001.00739
OVARYMitochondrial electron transport, cytochrome c to oxygen →+0.070+0.335<.001<.00139
BLOOD_LeukemiaPositive regulation of double-strand break repair →+0.054+0.169<.001<.00139
SKINVentricular cardiac muscle cell action potential →-0.162-0.233<.001.00338
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,931 associations by consensus.

Regulation of translational initiation by SCN3B expression — OVARY

Box plot of Regulation of translational initiation in SCN3B-low vs SCN3B-high samples in OVARY.

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Exploration