SCN2B

Across TCGA cell cohorts, SCN2B RNA expression is significantly associated with the go_rna of many other GO terms, with 227 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SCN2B-associated GO terms across cancer lineages are Regulation of cell cycle G1/S phase transition, Regulation of hydrogen peroxide metabolic process, and Negative regulation of ceramide biosynthetic process. Each is linked with SCN2B in more than 4 cancer types. Because this analysis shows association rather than direction, both SCN2B-to-partner and partner-to-SCN2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell cycle G1/S phase transition grouped by SCN2B-low versus SCN2B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN2B→partner) and Y-score (partner→SCN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of cell cycle G1/S phase transition →	+0.034	+0.204	.005	.007	3	5
CNS	Regulation of hydrogen peroxide metabolic process →	+0.108	+0.070	.001	.006	3	3
CNS	Negative regulation of ceramide biosynthetic process →	+0.103	+0.054	<.001	.003	3	3
BLOOD_Leukemia	Regulation of DNA repair →	+0.040	+0.080	<.001	.009	3	3
UPPER_AERODIGESTIVE_TRACT	Disruption of anatomical structure in another organism →	-0.114	-0.053	.002	.003	3	2
UPPER_AERODIGESTIVE_TRACT	Disruption of cell in another organism →	-0.129	-0.053	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 227 associations by consensus.

Regulation of cell cycle G1/S phase transition by SCN2B expression — OVARY

Explore this box plot interactively →