SCN2A

Across TCGA patient cohorts, SCN2A RNA expression is significantly associated with the RNA expression of many other genes, with 15,082 significant associations in total. PCPG shows the largest number of these associations.

The most reproducible SCN2A-associated genes across cancer lineages are SCN3A, CSRNP3, and FAM66C. Each is linked with SCN2A in more than 27 cancer types. Because this analysis shows association rather than direction, both SCN2A-to-partner and partner-to-SCN2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCN2A versus SCN3A in SCLC, with a Pearson correlation of 0.38.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN2A→partner) and Y-score (partner→SCN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	SCN3A →	+1.963	+1.795	.002	.003	1	28
PCPG	CSRNP3 →	+1.158	+0.952	<.001	<.001	3	24
TGCT	FAM66C →	+0.754	+0.550	<.001	<.001	3	22
UCS	BBS10 →	+1.182	+0.741	<.001	.001	3	21
LGG	TSPYL4 →	+0.777	+1.436	<.001	<.001	3	21
PCPG	PLEKHM3 →	+1.083	+0.778	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,082 associations by consensus.

SCN2A vs SCN3A — SCLC

Explore this scatter interactively →