SCN11A

Across TCGA patient cohorts, SCN11A RNA expression is significantly associated with the protein abundance of many other proteins, with 9,732 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SCN11A-associated proteins across cancer lineages are ANXA6, MFAP5, and OLFML1. Each is linked with SCN11A in more than 4 cancer types. Because this analysis shows association rather than direction, both SCN11A-to-partner and partner-to-SCN11A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCN11A versus ANXA6 in COAD, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCN11A→partner) and Y-score (partner→SCN11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ANXA6 →	+0.464	+0.097	<.001	<.001	3	4
CCRCC	MFAP5 →	+0.875	+0.285	<.001	<.001	3	4
COAD	OLFML1 →	+0.748	+0.132	<.001	<.001	3	4
COAD	PGM5 →	+0.874	+0.078	<.001	.007	2	5
LSCC	MICALL1_S621 →	-0.825	-0.147	<.001	<.001	3	4
HNSC	PLCL1_T556 →	+0.743	+0.227	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,732 associations by consensus.

SCN11A vs ANXA6 — COAD

Explore this scatter interactively →