SCML1

Across TCGA cell cohorts, SCML1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,293 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SCML1-associated GO terms across cancer lineages are DNA synthesis involved in DNA repair, Type 2 mitophagy, and Negative regulation of mitotic cell cycle phase transition. Each is linked with SCML1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SCML1-to-partner and partner-to-SCML1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA synthesis involved in DNA repair grouped by SCML1-low versus SCML1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCML1→partner) and Y-score (partner→SCML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	DNA synthesis involved in DNA repair →	+0.068	+0.695	.003	.004	3	8
SKIN	Type 2 mitophagy →	+0.115	+0.691	<.001	.001	3	8
BREAST	Negative regulation of mitotic cell cycle phase transition →	+0.060	+1.576	.003	.002	3	7
BREAST	DNA biosynthetic process →	+0.059	+1.809	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Post-Golgi vesicle-mediated transport →	+0.073	+1.173	<.001	.003	2	8
LUNG_NSCLC_LUSC	Negative regulation of cell cycle process →	+0.050	+1.021	.006	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,293 associations by consensus.

DNA synthesis involved in DNA repair by SCML1 expression — KIDNEY

Explore this box plot interactively →