SCGB3A2

Across TCGA patient cohorts, SCGB3A2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,712 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SCGB3A2-associated genes across cancer lineages are SNORA9B, NPR3, and TOP2A. Each is linked with SCGB3A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCGB3A2-to-partner and partner-to-SCGB3A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCGB3A2 versus SNORA9B in HNSC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB3A2→partner) and Y-score (partner→SCGB3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNORA9B →	-1.013	-0.639	.001	.005	3	2
LSCC	NPR3 →	+0.855	+0.795	<.001	<.001	3	2
LUAD	TOP2A →	-0.789	-1.249	.005	.001	3	2
LSCC	SCN7A →	+1.082	+1.014	<.001	.002	3	2
LSCC	HASPIN →	-0.483	-0.924	.001	.001	3	2
LUAD	AURKB →	-0.555	-1.107	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,712 associations by consensus.

SCGB3A2 vs SNORA9B — HNSC

Explore this scatter interactively →