SCGB3A1

Across TCGA patient cohorts, SCGB3A1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,939 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SCGB3A1-associated genes across cancer lineages are GNA14, PIGR, and NWD1. Each is linked with SCGB3A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCGB3A1-to-partner and partner-to-SCGB3A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCGB3A1 versus GNA14 in LUAD, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB3A1→partner) and Y-score (partner→SCGB3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GNA14 →	+0.876	+0.916	.001	.006	3	3
LSCC	PIGR →	+2.377	+0.914	<.001	<.001	3	3
LSCC	NWD1 →	+0.921	+0.874	.002	<.001	3	3
HNSC	WFDC2 →	+1.747	+1.213	.002	<.001	3	2
LUAD	ZBTB16 →	+1.408	+1.011	<.001	.002	3	2
HNSC	NME5 →	+0.453	+1.031	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,939 associations by consensus.

SCGB3A1 vs GNA14 — LUAD

Explore this scatter interactively →