SCGB1C1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SCGB1C1 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCGB1C1-associated genes across cancer lineages are LINC01661, MTND5P20, and RNU6-819P. Each is linked with SCGB1C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCGB1C1-to-partner and partner-to-SCGB1C1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCGB1C1→partner) and Y-score (partner→SCGB1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC01661 →+0.115+5.097<.001.00831
SKCMMTND5P20 →+0.378+5.362<.001.00531
COADRNU6-819P →+0.427+7.741<.001.00931
COADACTR3BP7 →+0.044+7.741<.001.00931
COADYWHAQP9 →+0.107+7.741.005.00931
LUADMIR124-3 →+0.363+7.930<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

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