SCG3

Across TCGA patient cohorts, SCG3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,162 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCG3-associated proteins across cancer lineages are PGRMC2_S104, CAST_S499, and COL15A1. Each is linked with SCG3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SCG3-to-partner and partner-to-SCG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCG3 versus PGRMC2_S104 in LUAD, with a Pearson correlation of -0.20.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCG3→partner) and Y-score (partner→SCG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PGRMC2_S104 →	-1.012	-0.494	<.001	<.001	3	5
LUAD	CAST_S499 →	-0.824	-0.838	<.001	.003	3	5
CCRCC	COL15A1 →	+0.396	+0.299	.001	<.001	3	4
CCRCC	FEZ1_S58 →	+0.422	+0.259	.003	.009	3	4
GBM	TMOD2 →	+0.346	+1.131	<.001	<.001	3	4
LSCC	MYEF2 →	+0.670	+0.327	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,162 associations by consensus.

SCG3 vs PGRMC2_S104 — LUAD

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