SCG3

Across TCGA patient cohorts, SCG3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,405 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SCG3-associated genes across cancer lineages are NPDC1, DNAJC6, and SLC8A2. Each is linked with SCG3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCG3-to-partner and partner-to-SCG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCG3 versus NPDC1 in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCG3→partner) and Y-score (partner→SCG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NPDC1 →	+1.154	+1.241	.008	.003	3	3
BRCA	DNAJC6 →	+1.450	+1.907	.001	.001	3	3
BRCA	SLC8A2 →	+2.116	+2.033	.001	.002	3	3
BRCA	GRIA2 →	+3.814	+1.931	.008	.008	3	3
PDAC	FFAR1 →	+1.282	+1.176	<.001	<.001	3	3
BRCA	FBXL16 →	+1.790	+1.558	.003	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,405 associations by consensus.

SCG3 vs NPDC1 — BRCA

Explore this scatter interactively →