SCG3

Across TCGA cell cohorts, SCG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,794 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SCG3-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Stress granule assembly, and Sensory perception of mechanical stimulus. Each is linked with SCG3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SCG3-to-partner and partner-to-SCG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SCG3-low versus SCG3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCG3→partner) and Y-score (partner→SCG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of myoblast fusion →	+0.120	+0.073	<.001	.001	3	7
BREAST	Stress granule assembly →	+0.094	+0.098	<.001	.002	3	7
BREAST	Sensory perception of mechanical stimulus →	-0.074	-0.103	<.001	.001	3	6
BREAST	Microtubule organizing center organization →	+0.074	+0.079	<.001	.005	3	6
BLOOD_Lymphoma	Positive regulation of DNA repair →	+0.052	+0.063	<.001	<.001	3	6
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.104	+0.149	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,794 associations by consensus.

Negative regulation of myoblast fusion by SCG3 expression — BREAST

Explore this box plot interactively →