Across TCGA cell cohorts, SCFD2 mutation is significantly associated with the mutation status of many other genes, with 1,707 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCFD2-associated genes across cancer lineages are TP53BP2, SLAMF6, and ZNF354C. Each is linked with SCFD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SCFD2-to-partner and partner-to-SCFD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCFD2→partner) and Y-score (partner→SCFD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TP53BP2 →	+4.392	+4.392	.009	.009	1	3
BLOOD_Leukemia	SLAMF6 →	+5.894	+5.321	.002	.002	1	3
SKIN	ZNF354C →	+4.392	+4.392	.009	.009	1	3
BLOOD_Leukemia	SYTL3 →	+4.894	+4.894	.004	.004	1	3
BLOOD_Leukemia	SYNPO2 →	+2.779	+4.326	.006	.006	1	3
BLOOD_Leukemia	SKIDA1 →	+3.894	+5.247	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,707 associations by consensus.

Exploration

SCFD2 survival (RNA) · tumor vs normal (RNA) · all SCFD2 data types