SCFD1

Across TCGA patient cohorts, SCFD1 mutation is significantly associated with the RNA expression of many other genes, with 2,316 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCFD1-associated genes across cancer lineages are RN7SKP101, LINC00380, and S100A11P10. Each is linked with SCFD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCFD1-to-partner and partner-to-SCFD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP101 grouped by SCFD1-low versus SCFD1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCFD1→partner) and Y-score (partner→SCFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP101 →	+0.069	+5.307	<.001	.001	3	2
BLCA	LINC00380 →	+0.218	+5.632	<.001	.001	3	2
BLCA	S100A11P10 →	+0.091	+4.444	<.001	.006	3	2
BLCA	ELAVL4-AS1 →	+0.034	+3.792	.008	.004	3	2
COAD	RN7SKP261 →	+0.309	+3.484	<.001	.006	3	2
LUSC	KRTAP21-1 →	+0.243	+4.706	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,316 associations by consensus.

RN7SKP101 by SCFD1 expression — BLCA

Explore this box plot interactively →