SCFD1

Across TCGA cell cohorts, SCFD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,168 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SCFD1-associated GO terms across cancer lineages are Monoubiquitinated protein deubiquitination, Vesicle tethering to Golgi, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with SCFD1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SCFD1-to-partner and partner-to-SCFD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monoubiquitinated protein deubiquitination grouped by SCFD1-low versus SCFD1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCFD1→partner) and Y-score (partner→SCFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Monoubiquitinated protein deubiquitination →	+0.149	+1.024	.002	<.001	3	14
OESOPHAGUS	Vesicle tethering to Golgi →	+0.137	+1.028	<.001	.001	3	12
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.115	+0.759	<.001	.002	3	12
OESOPHAGUS	SRP-dependent cotranslational protein targeting to membrane, translocation →	+0.134	+0.863	.004	.008	2	11
OESOPHAGUS	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.142	+0.887	<.001	<.001	3	10
BONE	SRP-dependent cotranslational protein targeting to membrane →	+0.121	+0.841	.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,168 associations by consensus.

Monoubiquitinated protein deubiquitination by SCFD1 expression — URINARY_TRACT

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