SCFD1

Across TCGA cell cohorts, SCFD1 mutation is significantly associated with the RNA expression of many other genes, with 976 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCFD1-associated genes across cancer lineages are SOX14, KRTAP4-11, and OR7G1. Each is linked with SCFD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCFD1-to-partner and partner-to-SCFD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SOX14 grouped by SCFD1-low versus SCFD1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCFD1→partner) and Y-score (partner→SCFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SOX14 →	+0.012	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP4-11 →	+0.045	+5.209	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR7G1 →	+0.017	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	CCL18 →	+0.026	+4.212	.005	.007	3	1
LARGE_INTESTINE	GCAT →	+1.262	+3.584	<.001	<.001	3	1
LARGE_INTESTINE	CCDC134 →	+0.629	+3.301	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 976 associations by consensus.

SOX14 by SCFD1 expression — BLOOD_Lymphoma

Explore this box plot interactively →