SCAT2

Across TCGA patient cohorts, SCAT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,276 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SCAT2-associated proteins across cancer lineages are TOP2A, MDC1, and PARP1. Each is linked with SCAT2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SCAT2-to-partner and partner-to-SCAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCAT2 versus TOP2A in LUAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAT2→partner) and Y-score (partner→SCAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOP2A →	+0.991	+0.655	<.001	<.001	3	8
LSCC	MDC1 →	+0.388	+0.707	<.001	<.001	3	7
HNSC	PARP1 →	+0.568	+1.115	<.001	<.001	3	7
LUAD	TOP2A_S1247 →	+1.297	+0.689	<.001	<.001	3	7
LSCC	USP39 →	+0.296	+0.617	<.001	<.001	3	7
LSCC	SUPT6H →	+0.244	+0.599	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,276 associations by consensus.

SCAT2 vs TOP2A — LUAD

Explore this scatter interactively →