SCARNA14

Across TCGA pan-cancer cohorts, SCARNA14 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SCARNA14 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SCARNA14 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SCARNA14 expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

ACC, LUSC, and THCA are the cancer types where SCARNA14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	II,III,IV	0.137	0.753	<.001	48	view →
LUSC	DFS	Tertile	All	0.276	0.424	.006	33	view →
THCA	OS	Tertile	IV	0.626	1.000	.002	24	view →
BLCA	DFS	Tertile	IV	0.599	0.317	.015	18	view →
TGCT	OS	Tertile	All	0.847	0.991	.003	18	view →
BRCA	OS	Tertile	III,IV	1.000	0.892	.037	12	view →
LUAD	DFS	Tertile	II,III,IV	0.766	0.474	.024	12	view →
OV	DFS	Quartile	III,IV	0.590	0.492	.022	10	view →
SKCM	DFS	Tertile	II,III,IV	0.117	0.242	.013	9	view →
READ	OS	Tertile	III,IV	0.328	0.750	.012	9	view →
KICH	OS	Tertile	All	0.402	0.876	.039	6	view →
THYM	DFS	Tertile	II,III,IV	1.000	0.613	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SCARNA14–ACC (DFS)

Open the ACC breakdown →