SCARNA14

Across TCGA pan-cancer cohorts, SCARNA14 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of SCARNA14’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where SCARNA14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SCARNA14 is over-expressed in tumor.

BRCA, LUSC, and COAD are the cancer types where SCARNA14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SCARNA14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.128	.043	4	view →
LUSC	All	All	+0.126	.006	4	view →
COAD	All	All	+0.157	.011	3	view →
HNSC	All	III,IV	+0.110	.025	3	view →
STAD	All	IV	+0.760	.014	1	view →
ESCA	Female	All	+0.336	<.001	1	view →
LUAD	All	II,III,IV	+0.243	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

SCARNA14–BRCA

Open the BRCA breakdown →