SCARA5

Across TCGA cell cohorts, SCARA5 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCARA5-associated genes across cancer lineages are KHDC3L, KHDRBS2, and KRTAP4-6. Each is linked with SCARA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCARA5-to-partner and partner-to-SCARA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KHDC3L grouped by SCARA5-low versus SCARA5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCARA5→partner) and Y-score (partner→SCARA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KHDC3L →	+0.190	+4.096	<.001	.001	3	2
OESOPHAGUS	KHDRBS2 →	+0.603	+4.906	<.001	.006	3	1
SKIN	KRTAP4-6 →	+0.045	+6.000	<.001	<.001	3	1
LARGE_INTESTINE	TMSB4Y →	+1.272	+3.556	<.001	.007	3	1
LARGE_INTESTINE	ITGAD →	+0.009	+2.925	.003	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.020	+4.029	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

KHDC3L by SCARA5 expression — BLOOD_Leukemia

Explore this box plot interactively →