SCAMP2

Across TCGA pan-cancer cohorts, SCAMP2 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated SCAMP2 data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SCAMP2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SCAMP2 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, UCEC, and PDAC are the cancer types where SCAMP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.889	.033	12	view →
UCEC	OS	Quartile	III,IV	1.000	0.288	.040	12	view →
PDAC	DFS	Median	All	0.248	0.434	.019	8	view →
HNSC	OS	Quartile	II,III,IV	0.895	0.643	.015	6	view →
LUAD	OS	Tertile	All	0.797	1.000	.023	5	view →
GBM	DFS	Median	All	0.703	0.791	.034	3	view →
LSCC	DFS	Median	II,III,IV	0.555	0.812	.029	2	view →
CCRCC	DFS	Median	II,III,IV	1.000	0.542	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

SCAMP2–COAD (DFS)

Open the COAD breakdown →