SCAMP2

Across TCGA patient cohorts, SCAMP2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCAMP2-associated genes across cancer lineages are CD8+ naive T-cells, CD8+ Tcm, and lymphatic Endothelial cells. Each is linked with SCAMP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCAMP2-to-partner and partner-to-SCAMP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by SCAMP2-low versus SCAMP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAMP2→partner) and Y-score (partner→SCAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.027	+2.823	.035	.036	3	1
UCEC	CD8+ Tcm →	+0.022	+2.198	.016	.039	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.129	.034	.019	3	1
UCEC	Class-switched memory B-cells →	-0.064	-3.584	.020	.003	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD8+ naive T-cells by SCAMP2 expression — UCEC

Explore this box plot interactively →