Across TCGA patient cohorts, SCAF8 mutation is significantly associated with the RNA expression of many other genes, with 4,913 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCAF8-associated genes across cancer lineages are RARS2, MIR4667, and MIR3115. Each is linked with SCAF8 in more than 3 cancer types. Because this analysis shows association rather than direction, both SCAF8-to-partner and partner-to-SCAF8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF8→partner) and Y-score (partner→SCAF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RARS2 →	+0.358	+1.459	<.001	.001	3	4
KIRP	MIR4667 →	+0.447	+4.967	<.001	.009	3	3
LUAD	MIR3115 →	+0.320	+3.285	.009	.009	3	3
UCEC	VTI1A →	+0.238	+2.032	.006	.001	3	3
LUSC	GUF1 →	+0.606	+3.369	.001	.005	3	3
UCEC	ZUP1 →	+0.357	+2.043	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,913 associations by consensus.

Exploration

SCAF8 survival (RNA) · tumor vs normal (RNA) · all SCAF8 data types