SCAF11

Across TCGA patient cohorts, SCAF11 mutation is significantly associated with the RNA expression of many other genes, with 4,052 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCAF11-associated genes across cancer lineages are LINC02307, ING2, and DAZAP1. Each is linked with SCAF11 in more than 3 cancer types. Because this analysis shows association rather than direction, both SCAF11-to-partner and partner-to-SCAF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02307 grouped by SCAF11-low versus SCAF11-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCAF11→partner) and Y-score (partner→SCAF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	LINC02307 →	+0.558	+2.149	<.001	.009	3	4
UCEC	ING2 →	+0.300	+1.249	.007	.006	3	4
UCEC	DAZAP1 →	+0.215	+1.716	.004	.002	3	4
UCEC	C1QBP →	+0.496	+1.722	<.001	<.001	3	3
UCEC	BAG2 →	+0.648	+1.893	<.001	<.001	3	3
UCEC	MRPS27 →	+0.313	+1.758	.006	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,052 associations by consensus.

LINC02307 by SCAF11 expression — LUSC

Explore this box plot interactively →