SBSPON

Across TCGA patient cohorts, SBSPON mutation is significantly associated with the RNA expression of many other genes, with 272 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SBSPON-associated genes across cancer lineages are RN7SL831P, RNU1-84P, and OR2T5. Each is linked with SBSPON in more than 1 cancer types. Because this analysis shows association rather than direction, both SBSPON-to-partner and partner-to-SBSPON results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL831P grouped by SBSPON-low versus SBSPON-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSPON→partner) and Y-score (partner→SBSPON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL831P →	+0.103	+4.219	<.001	.006	3	2
COAD	RNU1-84P →	+1.267	+7.741	<.001	.009	3	2
COAD	OR2T5 →	+0.209	+7.741	<.001	.009	3	2
COAD	RNY4P18 →	+0.734	+7.741	<.001	.009	3	2
COAD	RNU6ATAC41P →	+0.476	+7.741	<.001	.009	3	2
COAD	RNU6-1139P →	+0.401	+7.741	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 272 associations by consensus.

RN7SL831P by SBSPON expression — SKCM

Explore this box plot interactively →