Across TCGA cell cohorts, SBSN RNA expression is significantly associated with the RNA expression of many other genes, with 4,868 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SBSN-associated genes across cancer lineages are IL11, RAB11FIP5, and SERPINB7. Each is linked with SBSN in more than 6 cancer types. Because this analysis shows association rather than direction, both SBSN-to-partner and partner-to-SBSN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBSN→partner) and Y-score (partner→SBSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	IL11 →	+3.059	+2.096	<.001	.001	3	7
BONE	RAB11FIP5 →	+1.665	+2.073	<.001	.001	3	6
BONE	SERPINB7 →	+3.263	+2.367	.001	.003	3	6
BONE	BDKRB1 →	+2.787	+2.046	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	RAET1G →	+2.061	+3.024	<.001	<.001	3	5
BONE	HRH1 →	+2.773	+2.072	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,868 associations by consensus.

Exploration

SBSN survival (RNA) · tumor vs normal (RNA) · all SBSN data types