SBNO2

Across TCGA cell cohorts, SBNO2 mutation is significantly associated with the RNA expression of many other genes, with 1,141 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SBNO2-associated genes across cancer lineages are FBXW10, ASZ1, and RANBP9. Each is linked with SBNO2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SBNO2-to-partner and partner-to-SBNO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FBXW10 grouped by SBNO2-low versus SBNO2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBNO2→partner) and Y-score (partner→SBNO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FBXW10 →	+0.177	+3.023	<.001	<.001	3	3
OVARY	ASZ1 →	+0.058	+3.169	<.001	.001	3	2
BLOOD_Leukemia	RANBP9 →	+0.695	+3.199	.003	.007	3	2
LARGE_INTESTINE	ADNP2 →	+0.676	+2.850	.001	<.001	3	2
LARGE_INTESTINE	CEP76 →	+0.645	+3.321	.001	.003	3	2
LARGE_INTESTINE	TRIM37 →	+0.526	+3.459	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,141 associations by consensus.

FBXW10 by SBNO2 expression — LARGE_INTESTINE

Explore this box plot interactively →