SBNO2

Across TCGA pan-cancer cohorts, SBNO2 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of SBNO2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SBNO2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SBNO2 is over-expressed in tumor.

COAD, KIRC, and STAD are the cancer types where SBNO2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SBNO2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.412	<.001	11	view →
KIRC	Female	All	+1.127	<.001	11	view →
STAD	Male	II,III,IV	+1.503	<.001	8	view →
BLCA	Male	III,IV	+1.358	<.001	7	view →
LIHC	All	II,III,IV	+0.732	<.001	7	view →
KIRP	All	All	+0.647	.001	7	view →
BRCA	All	II,III,IV	+0.490	<.001	6	view →
CHOL	All	All	+2.414	<.001	5	view →
ESCA	All	All	+1.321	.001	5	view →
READ	All	All	+1.203	<.001	5	view →
LUAD	All	All	+0.457	.002	5	view →
HNSC	All	All	+0.519	.003	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

SBNO2–COAD

Open the COAD breakdown →