Across TCGA pan-cancer cohorts, SBK2 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated SBK2 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SBK2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SBK2 expression acts as an unfavorable survival marker.

HNSC are the cancer types where SBK2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.503	0.912	.001	28	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: SBK2 tumor-vs-normal RNA expression · all SBK2 data types