Across TCGA cell cohorts, SBK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 821 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SBK2-associated GO terms across cancer lineages are Negative regulation of Rho protein signal transduction, Positive regulation of protein transport, and NMDA glutamate receptor clustering. Each is linked with SBK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SBK2-to-partner and partner-to-SBK2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SBK2→partner) and Y-score (partner→SBK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of Rho protein signal transduction →	+0.099	+0.077	<.001	.001	3	4
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein transport →	+0.041	+0.048	.004	.003	3	4
BLOOD_Leukemia	NMDA glutamate receptor clustering →	+0.781	+0.053	.001	.007	3	3
CNS	Positive regulation of telomere maintenance via telomere lengthening →	+0.042	+0.451	.002	.008	3	3
CNS	Mucus secretion →	-0.814	-0.582	<.001	.007	3	3
SOFT_TISSUE	Actin nucleation →	-0.129	-1.769	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 821 associations by consensus.

Exploration

SBK2 survival (RNA) · tumor vs normal (RNA) · all SBK2 data types