SBK1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SBK1 mutation is significantly associated with the RNA expression of many other genes, with 546 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SBK1-associated genes across cancer lineages are RN7SL812P, RNVU1-2A, and HAO1. Each is linked with SBK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SBK1-to-partner and partner-to-SBK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SBK1→partner) and Y-score (partner→SBK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRN7SL812P →+0.559+3.198<.001.00932
LUADRNVU1-2A →+1.693+3.821<.001.00732
SKCMHAO1 →+0.300+2.424.005.00132
SKCMAPTX →+0.568+2.813<.001.00132
BLCASNORD115-1 →+0.388+7.640<.001.00932
SKCMMIR301A →+0.157+2.574<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 546 associations by consensus.

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