Across TCGA patient cohorts, SAXO2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,130 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SAXO2-associated genes across cancer lineages are BPIFB1, BRCA2, and CFAP52. Each is linked with SAXO2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SAXO2-to-partner and partner-to-SAXO2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAXO2→partner) and Y-score (partner→SAXO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BPIFB1 →	+2.246	+0.624	<.001	<.001	3	3
UCEC	BRCA2 →	-0.788	-0.771	.001	<.001	3	3
UCEC	CFAP52 →	+1.634	+0.774	.005	.003	3	3
UCEC	RSPH10B2 →	+0.759	+0.623	<.001	.004	3	3
UCEC	VNN3 →	+1.356	+0.756	.002	.002	3	3
OV	LYVE1 →	+1.981	+0.459	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,130 associations by consensus.

Exploration

SAXO2 survival (RNA) · tumor vs normal (RNA) · all SAXO2 data types