Across TCGA patient cohorts, SATB1 mutation is significantly associated with the RNA expression of many other genes, with 4,847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SATB1-associated genes across cancer lineages are RN7SL248P, OXSM, and BUB3. Each is linked with SATB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SATB1-to-partner and partner-to-SATB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SATB1→partner) and Y-score (partner→SATB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.043	+2.552	<.001	.003	3	3
UCEC	OXSM →	+0.332	+2.392	<.001	<.001	3	3
UCEC	BUB3 →	+0.434	+2.323	<.001	<.001	3	3
UCEC	SUPV3L1 →	+0.329	+1.595	<.001	<.001	3	3
UCEC	MYO19 →	+0.513	+2.524	<.001	<.001	3	3
UCEC	MICU1 →	+0.265	+1.462	.005	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,847 associations by consensus.

Exploration

SATB1 survival (RNA) · tumor vs normal (RNA) · all SATB1 data types