SAT1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SAT1 protein abundance is significantly associated with the RNA expression of many other genes, with 968 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SAT1-associated genes across cancer lineages are BMP8B, DSTYK, and XIAP. Each is linked with SAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SAT1-to-partner and partner-to-SAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SAT1 versus BMP8B in UCEC, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SAT1→partner) and Y-score (partner→SAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBMP8B →-1.211-0.715.003.00232
UCECDSTYK →-0.681-0.743.009.00932
UCECXIAP →-0.676-0.860.003.00331
UCECZC2HC1A →-1.036-0.916.005.00231
UCECKLC3 →-1.449-0.968.007<.00131
UCECAGR2 →+3.963+0.685<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 968 associations by consensus.

SAT1 vs BMP8B — UCEC

Per-sample scatter of SAT1 vs BMP8B in UCEC (Pearson r = -0.64).

Explore this scatter interactively →

Exploration