SAT1

Across TCGA cell cohorts, SAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,872 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SAT1-associated GO terms across cancer lineages are Polyamine catabolic process, Microtubule depolymerization, and Spermidine metabolic process. Each is linked with SAT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SAT1-to-partner and partner-to-SAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Polyamine catabolic process grouped by SAT1-low versus SAT1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SAT1→partner) and Y-score (partner→SAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Polyamine catabolic process →	+0.304	+2.522	<.001	<.001	3	14
STOMACH	Microtubule depolymerization →	-0.137	-1.172	<.001	.007	3	11
BONE	Spermidine metabolic process →	+0.134	+2.655	<.001	<.001	3	11
BONE	Rab protein signal transduction →	+0.112	+2.872	.001	.001	3	10
BONE	Response to steroid hormone →	+0.108	+2.770	<.001	<.001	3	10
BONE	Regulation of protein localization to plasma membrane →	+0.147	+2.758	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,872 associations by consensus.

Polyamine catabolic process by SAT1 expression — LUNG_SCLC

Explore this box plot interactively →