SASS6

Across TCGA patient cohorts, SASS6 protein abundance is significantly associated with the RNA expression of many other genes, with 5,985 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SASS6-associated genes across cancer lineages are NCAPD2, CDKN3, and VRK1. Each is linked with SASS6 in more than 4 cancer types. Because this analysis shows association rather than direction, both SASS6-to-partner and partner-to-SASS6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SASS6 versus NCAPD2 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SASS6→partner) and Y-score (partner→SASS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPD2 →	+0.775	+0.374	.001	.003	3	5
LUAD	CDKN3 →	+0.990	+0.484	<.001	<.001	3	4
LUAD	VRK1 →	+0.716	+0.529	<.001	.001	3	4
LUAD	GINS1 →	+1.367	+0.623	<.001	<.001	3	4
LUAD	MYBL2 →	+1.858	+0.680	<.001	<.001	3	4
LUAD	E2F1 →	+1.335	+0.573	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,985 associations by consensus.

SASS6 vs NCAPD2 — UCEC

Explore this scatter interactively →