SART1

Across TCGA patient cohorts, SART1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,773 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SART1-associated genes across cancer lineages are RPP40, WDR74, and CCDC58. Each is linked with SART1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SART1-to-partner and partner-to-SART1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SART1 versus RPP40 in HNSC, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SART1→partner) and Y-score (partner→SART1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPP40 →	+0.815	+0.173	<.001	.001	3	7
BRCA	WDR74 →	+0.485	+0.167	<.001	<.001	3	7
HNSC	CCDC58 →	+0.804	+0.170	<.001	.005	3	7
LSCC	LIN9 →	+0.691	+0.225	<.001	<.001	3	7
OV	CMSS1 →	+0.680	+0.251	<.001	<.001	3	7
HNSC	SNHG1 →	+0.732	+0.174	.002	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,773 associations by consensus.

SART1 vs RPP40 — HNSC

Explore this scatter interactively →