SARDH

Across TCGA patient cohorts, SARDH protein abundance is significantly associated with the RNA expression of many other genes, with 11,412 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SARDH-associated genes across cancer lineages are CENPH, STMN1, and DBH. Each is linked with SARDH in more than 4 cancer types. Because this analysis shows association rather than direction, both SARDH-to-partner and partner-to-SARDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SARDH versus CENPH in OV, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SARDH→partner) and Y-score (partner→SARDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CENPH →	-0.891	-1.242	<.001	<.001	3	5
BRCA	STMN1 →	-0.872	-0.474	<.001	.002	3	5
UCEC	DBH →	+0.742	+0.422	.003	<.001	3	5
LSCC	SAMD1 →	-0.485	-0.378	<.001	<.001	3	5
LSCC	BUB3 →	-0.512	-0.305	<.001	.004	3	5
BRCA	DBH-AS1 →	+0.824	+0.559	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,412 associations by consensus.

SARDH vs CENPH — OV

Explore this scatter interactively →