SARDH

Across TCGA cell cohorts, SARDH protein abundance is significantly associated with the RNA expression of many other genes, with 1,893 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SARDH-associated genes across cancer lineages are DEF8, CCNYL1, and PACSIN2. Each is linked with SARDH in more than 1 cancer types. Because this analysis shows association rather than direction, both SARDH-to-partner and partner-to-SARDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SARDH versus DEF8 in BLOOD_Lymphoma, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SARDH→partner) and Y-score (partner→SARDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DEF8 →	+2.511	+1.782	.002	<.001	3	2
BLOOD_Lymphoma	CCNYL1 →	+0.887	+1.615	.009	.001	3	2
BLOOD_Leukemia	PACSIN2 →	+0.382	+0.822	.005	.006	3	1
BLOOD_Leukemia	MANBAL →	+0.495	+1.026	.007	.005	3	1
BLOOD_Leukemia	EHD4 →	+1.913	+1.549	.001	.002	3	1
BLOOD_Leukemia	ZKSCAN1 →	+0.716	+0.988	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,893 associations by consensus.

SARDH vs DEF8 — BLOOD_Lymphoma

Explore this scatter interactively →