SARDH

Across TCGA cell cohorts, SARDH protein abundance is significantly associated with the go_rna of many other GO terms, with 1,092 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SARDH-associated GO terms across cancer lineages are Regulation of membrane invagination, Positive regulation of membrane invagination, and Icosanoid secretion. Each is linked with SARDH in more than 1 cancer types. Because this analysis shows association rather than direction, both SARDH-to-partner and partner-to-SARDH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of membrane invagination grouped by SARDH-low versus SARDH-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SARDH→partner) and Y-score (partner→SARDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of membrane invagination →	+0.166	+1.566	<.001	<.001	3	2
BLOOD_Lymphoma	Positive regulation of membrane invagination →	+0.178	+1.700	<.001	<.001	3	2
BLOOD_Lymphoma	Icosanoid secretion →	+0.103	+1.388	.005	.001	3	2
BLOOD_Lymphoma	Pyridoxal 5'-phosphate metabolic process →	-0.107	-1.399	.002	.004	3	2
BLOOD_Lymphoma	Leukocyte degranulation →	+0.098	+1.451	<.001	<.001	3	2
BLOOD_Lymphoma	Regulation of phagocytosis, engulfment →	+0.166	+1.566	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,092 associations by consensus.

Regulation of membrane invagination by SARDH expression — BLOOD_Lymphoma

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